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  1. #1
    Thailand Expat misskit's Avatar
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    Groundbreaking blood test can detect cancer years before symptoms appear

    A new blood test can detect various types of cancer years before previously possible with traditional detection methods, according to a new research published in the scientific journal Nature Communications.


    Early detection of cancer has the potential to significantly decrease death rates caused by the disease. Scientists have tried for years to develop a cancer screening-test that would reliably detect malignancy potential before tumor cells have the chance to spread, making treatment more effective. But until today, most attempts were unsuccessful or had partial results at best.

    Developed by a Sino-US startup, the groundbreaking new blood test is referred to as PanSeer. It was developed by an international team of scientists at the University of California, who were successfully able to diagnose five different types of cancer long before symptoms appeared in the patients it tested.


    The five types of cancer that PanSeer can currently detect are stomach cancer, esophageal cancer, bowel cancer, lung cancer and liver cancer, all fairly common.


    The test is based on a technique that was developed over a decade and allows detection of malignant tumors in their early stages, which haven't led to any symptoms yet and were thus undetectable with previous methods.


    Previous detections methods typically involved researchers collecting blood samples from people already diagnosed with the disease.


    The new study on the other hand, included a 10-year health survey conducted between 2007-2017 that took blood samples from more than 120,000 healthy people in China, collecting samples from people before they had presented any signs of having cancer.

    The detection technique is based on a biological process called DNA methylation analysis, which screens for DNA signatures specific to different cancers and identifies locations that have the greatest chance of signaling the presence of cancer. A special algorithm then compiles the findings and presents an indication of a person's likelihood of developing the disease.

    “What we showed is: up to four years before these people walk into the hospital, there are already signatures in their blood that show they have cancer,” says Kun Zhang, a bioengineer at the University of California, San Diego, and a co-author of the study. “That’s never been done before.”


    The test managed to detect early signs of cancer in 95% of the 605 patients who didn't show any symptoms when being tested but developed cancer up to four years later.


    The researchers hope that PanSeer or a similar blood test will become a standard annual test but noted that further and more comprehensive studies need to be done before that can happen.

    Groundbreaking blood test can detect cancer years before symptoms appear - The Jerusalem Post

  2. #2
    Thailand Expat jabir's Avatar
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    Surely the last thing the multi billion $ cancer industry want is an effective cure or scan; if it works, they will buy it and shelve it, or the Chinese or Russians will nick it, or maybe I'm too cynical.

  3. #3
    Custom user Neverna's Avatar
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    Developed by a Sino-US startup
    Wait 'til Trump hears about that!

  4. #4
    The Fool on the Hill bowie's Avatar
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    Not to get too excited, but, how about false positives? Scare the hell out of someone who did not nor will not develop cancer.

    Now, what will a positive result - actually mean? Well, basically, you are at risk of developing cancer. Who isn't? or, you are at a greater risk of developing cancer, kinda like a smoker.

    So, along the lines of jabirs post - the cancer companies can use this test to sell persons a new line of anti-cancer products...



    Now, on the positive side. Having a true positive result should put you on guard to monitor yourself with all preventative medical diagnostics and in such cases will be guaranteed to save lives and/or minimize pain. Then you open up the full debate concerning quality of life and the cure being worse than the disease. What price do put on extending a poor quality of life for a year or two or three?

  5. #5
    Hangin' Around cyrille's Avatar
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    Quote Originally Posted by bowie View Post
    Now, what will a positive result - actually mean?
    Quote Originally Posted by misskit View Post
    Scientists have tried for years to develop a cancer screening-test that would reliably detect malignancy potential before tumor cells have the chance to spread, making treatment more effective
    Quote Originally Posted by bowie View Post
    guaranteed to save lives and/or minimize pain.


    You answered your own question. And to jabir - obviously if that was the plan then this advance would not have been publicised.


    Jeez, you old boys are getting worse.

  6. #6
    The Fool on the Hill bowie's Avatar
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    Quote Originally Posted by cyrille View Post
    you old boys are getting worse
    yea, us ole grandpa types just thanking our lucky stars we got good ole eagle eye sherlock cy watching our backs... he don't miss a thing

    Way ta go Sherlock

  7. #7
    Hangin' Around cyrille's Avatar
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    Maybe quit wittering on with guff you don't actually believe (eg 'The tourism industry is finished and it's not coming back') or questions you know the answer to, then?

    Or is it a quiz, and we get the answers at the end of the week?

  8. #8
    Thailand Expat jabir's Avatar
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    Quote Originally Posted by cyrille View Post



    You answered your own question. And to jabir - obviously if that was the plan then this advance would not have been publicised.


    Jeez, you old boys are getting worse.
    You foolish immortal kids know it all and have zero respect for your elders; but think it through, with a bit of luck and something called smarts you could also avoid the alternative.

  9. #9
    The Fool on the Hill bowie's Avatar
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    Quote Originally Posted by cyrille View Post
    'The tourism industry is finished and it's not coming back'
    Not just me sherlock - industries going consensus - politicians and business leaders know tourism is a thing of the past - greatly reduced monies will be available and We, cannot wait for the vaccine.

    The damage is done. Economic/financial survival is now at stake. Tourism has gone the way of the 8 track tape player.

    Phuket learns the hard way

  10. #10
    Pedantic bastard
    nidhogg's Avatar
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    Quote Originally Posted by bowie View Post
    Not to get too excited, but, how about false positives? Scare the hell out of someone who did not nor will not develop cancer.

    Now, what will a positive result - actually mean? Well, basically, you are at risk of developing cancer. Who isn't? or, you are at a greater risk of developing cancer, kinda like a smoker.

    So, along the lines of jabirs post - the cancer companies can use this test to sell persons a new line of anti-cancer products...



    Now, on the positive side. Having a true positive result should put you on guard to monitor yourself with all preventative medical diagnostics and in such cases will be guaranteed to save lives and/or minimize pain. Then you open up the full debate concerning quality of life and the cure being worse than the disease. What price do put on extending a poor quality of life for a year or two or three?
    Sadly, pretty much none of what you write is even vaguely near correct. For most cancers it takes years (even decades) to go from cells that are abberant to a fully metastatic state. They are not saying they can detect who has the potenial - they are saying they can detect who has it at a very, very early stage. Big difference. The second thing is you are not talking a couple of years - you are probably talking decades. For nearly EVERY type of cancer, the earlier it is detected, the graeater the survival rate, and here they are basically talking even before the cancer has got going.

  11. #11
    Hangin' Around cyrille's Avatar
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    Quote Originally Posted by cyrille View Post
    'The tourism industry is finished and it's not coming back'
    Quote Originally Posted by bowie View Post
    politicians and business leaders know tourism is a thing of the past - greatly reduced monies will be available and We, cannot wait for the vaccine.
    *sigh*

    And from your link...

    "These will be our new economic engines which will function alongside the conventional tourism businesses," the governor said.

    Quote Originally Posted by nidhogg View Post
    Sadly, pretty much none of what you write is even vaguely near correct.
    And a health background such as yours is not essential to see it.

    There are holes in just about every single 'point' made. On the tourism argument he can't even remember what he conceded he was wrong on yesterday.

  12. #12
    The Fool on the Hill bowie's Avatar
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    Quote Originally Posted by nidhogg View Post
    They are not saying they can detect who has the potenial - they are saying they can detect who has it at a very, very early stage. Big difference.
    Yes, I understand your point. Yet in the article the methodology used is "indication of a person's likelihood of developing"
    Quote Originally Posted by misskit View Post
    A special algorithm then compiles the findings and presents an indication of a person's likelihood of developing the disease.
    Now, not to nitpick details and hopeful their work bears fruit, it is noted that...
    Quote Originally Posted by misskit View Post
    noted that further and more comprehensive studies need to be done

  13. #13
    Hangin' Around cyrille's Avatar
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    Quote Originally Posted by bowie View Post
    Yes, I understand your point. Yet in the article the methodology used is "indication of a person's likelihood of developing"

    Quote Originally Posted by misskit View Post
    “What we showed is: up to four years before these people walk into the hospital, there are already signatures in their blood that show they have cancer,”
    It can show up exactly what type of cancer is present, up to four years before the patient would have sought treatment.

  14. #14
    The Fool on the Hill bowie's Avatar
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    Quote Originally Posted by cyrille View Post
    On the tourism argument he can't even remember what he conceded he was wrong on yesterday.
    Cy, everyone has an interpretation. You believe that I believe tourism is gone. Tourism will always exist. But, as we move forward the amount of businesses and families supported by tourism will be seriously decreased. Everybody is still hoping that Covid is naught but a wrinkle and as soon as a vaccine is available all is well and we will be back to normal. The proverbial "New Normal".

    My believe is the economic damage caused by Covid will cripple tourism. Using the past revenue numbers as the yardstick. Todays worldwide massive unemployment figures, the fact that tourism dollars are discretionary spending, and the domino effect of the lack of discretionary spending by the unemployed. Tourism, is dead - not as a fire up the crematorium or dig the grave view. But as a viable investment vehicle.

    Gonna put money into a hotel, cruise line, airline, AirBnB, etc. Not I.

    Yet in the very recent past these were lucrative investment vehicles that provided reliable returns.

    Now, you want to argue fine details - the fine details are todays unemployment. And, a great many of the unemployed will not be returning to their old jobs. Their old jobs no longer exist. And will not come back.

  15. #15
    The Fool on the Hill bowie's Avatar
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    Quote Originally Posted by cyrille View Post
    It can show up exactly what type of cancer is present, up to four years before the patient would have sought treatment.
    That is a misquote

    Quote Originally Posted by misskit View Post
    The test managed to detect early signs of cancer in 95% of the 605 patients who didn't show any symptoms when being tested but developed cancer up to four years later.

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