@bld - your family was relatively hi-so in Laos (IMO). She was married to a farang who earned well, she/you guys had a nice house w/ pool, the kids studied in an international school, you took international trips every so often, you ate well, etc. I don't know her socio-economic status prior to marriage, but in Laos, she was a big fish in a small pond.
Then you guys tranaferred to Oz and became an ordinary middle class(?) family there. She wasn't "special" anymore - small fish in a big pond. That's a lot of adjustment, aside from the cultural/ language differences. I think she was overwhelmed with all the changes (and covid didn't help).
I hope with medication and treatment, she gets better soon. I also hope she gets ok enough for a trip back to Laos. Being in her homeland/ family might do wonders for her. All the best.