Vitamin E Link To Prostate Cancer Warning
Wednesday, 12th October 2011 01:04
Men have been warned to be wary of vitamin E supplements after research showed they significantly increase the risk of prostate cancer.
A study of more than 35,000 men found that those taking a high dose were 17% more likely to be diagnosed with the cancer than men taking dummy pills.
The effect continued long after men stopped taking the supplement.
US researchers writing in The Journal of the American Medical Association said men should be sceptical of health claims made for vitamins.
Lead investigator Dr Eric Klein, of the Cleveland Clinic in Chicago, said: "The implications of our observations are substantial.
"The increase in prostate cancer incidence demonstrates the potential for seemingly innocuous yet biologically active substances such as vitamins to do harm."
Researchers gave the men a dose of 400 international units (IU) of the vitamin a day. The recommended dietary allowance is 22.4 IU for adult men.
The researchers had been attempting to confirm previous studies that showed vitamin E and the mineral selenium could prevent prostate cancer.
Instead, they found that both supplements increase the likelihood of the disease, though in the case of selenium the risk was not statistically significant.
The scientists have been unable to find a biological reason why vitamin E makes men more susceptible to prostate cancer.
Dr Helen Rippon, of The Prostate Cancer Charity, said supplements are often - wrongly - seen as risk-free.
"Unfortunately for men, this means that a simple dietary supplement to protect against prostate cancer remains elusive," she said.
"Any man wishing to reduce their risk of the disease should stick to a healthy, balanced diet."
The Health Supplements Information Service, which represents vitamin manufacturers, said the dose used in the trial was "very high" and urged people to stick to recommended doses.
Link to related article