Diabetes risk gene from Neanderthals

[barbaro]

25 December 2013

Neanderthal genes 'survive in us'
Ancient humans interbred with us
Neanderthals 'could speak like us'
A gene variant that seems to increase the risk of diabetes in Latin Americans appears to have been inherited from Neanderthals, a study suggests.

We now know that modern humans interbred with a population of Neanderthals shortly after leaving Africa 60,000-70,000 years ago.

This means that Neanderthal genes are now scattered across the genomes of all non-Africans living today.

Details of the study appear in the journal Nature.

The gene variant was detected in a large genome-wide association study (GWAS) of more than 8,000 Mexicans and other Latin Americans. The GWAS approach looks at many genes in different individuals, to see whether they are linked with a particular trait.

People who carry the higher risk version of the gene are 25% more likely to have diabetes than those who do not, and people who inherited copies from both parents are 50% more likely to have diabetes.

The higher risk form of the gene - named SLC16A11 - has been found in up to half of people with recent Native American ancestry, including Latin Americans.

Drug hope

The variant is found in about 20% of East Asians and is rare in populations from Europe and Africa.

This could illuminate new pathways to target with drugs and a deeper understanding of the disease”

The elevated frequency of this variant in Latin Americans could account for as much as 20% of these populations' increased prevalence of type 2 diabetes - the origins of which are complex and poorly understood.

Entire: BBC News - Diabetes risk gene 'from Neanderthals'

[chassamui]

Have you considered asking the Mods for a sub forum Milky?

Hypochondria would be a good title. 55555

[barbaro]

Have you considered asking the Mods for a sub forum Milky?

I would ask if I thought they would give me one.

Hypochondria would be a good title. 55555

You think I think I'm a hypochon?

[Camel Toe]

I've been reading you for years and I think you have a whole string of disorders. Some might say you're a Freudian delight, but that's kind of cruel. Let's just say it's arrested development and let's let God sort out the name-calling and other details.

[barbaro]

I've been reading you for years and I think you have a whole string of disorders

So....you're another fan of mine.

I should add narcisstic personality to my "string of disorders."

[KiCanCummins]

It should have said

"Neanderthal genes 'survive in Thailand'" not in the US

[Camel Toe]

I'm not at all ashamed to have been descended from Neanders. They're European. Those other dudes are old world, like Blacks and Chinks 'n shit like that.

It's funny to note the first Neander remains found happened to be a man with arthritis. For practically a century we thought the race was these halfway-bipedic souls lookin like Rocky Horror.

[Rainfall]

Camel Toe, it says that gene is rarely found in Europeans. Seems the human ancestors crossbred in the Middle East, that trek with the mixes moved further East and eventually crossed the Bering Strait. Sapiens later arriving in Europe weren't screwed by Neanderthals anymore.

[barbaro]

Camel Toe, it says that gene is rarely found in Europeans. Seems the human ancestors crossbred in the Middle East, that trek with the mixes moved further East and eventually crossed the Bering Strait. Sapiens later arriving in Europe weren't screwed by Neanderthals anymore.

Rainfall,

You are correct and Camel is well.....usual.

Let him....or it....be.

[BaitongBoy]

I should add narcisstic personality to my "string of disorders."

As long as it's not the malignant variety...

[blue]

A few years ago, before about 2010 ,the experts declared the science was decided; Homo Sapiens and Neanderthals did not interbreed- they even had DNA comparisons to back up the ''consensus''.
It was obvious they were wrong and now more advanced DNA shows just how much so .
We were never screwed up by the Neanderthals , it was they who provided sapiens with creative and hard working genes etc,making Europeans the most wonderful race.
The Asian Race probably mixed with some other Neanderthal like peoples on their way East.