Guerrero (31-1-1, 18 knockouts) is a former world featherweight and super-featherweight champion who left the sport for 15 months after scoring a convincing decision over Michael Katsidis in April 2011. Guerrero took the break to care for his leukemia-stricken wife, Casey, whose illness is now in remission.
Guerrero flashed a glimpse of how his family concerns shaped him by beating hard-punching Selcuk Aydin in his comeback fight and welterweight debut in July 2012.
And now the ultimate test arrives with Mayweather (43-0, 26 KOs), famed for his quickness and defensive attributes. However, Mayweather's victory over Miguel Cotto in May 2012 left him more marked up than ever.